Catalog No.: PC-35710Not For Human Use, Lab Use Only.
SGC-iMLLT is the first small molecule chemical probe for the YEATS domain (YD) of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3) with Kd of 129 and 77 nM respectively, IC50 of 0.26 uM (MLLT1).
SGC-iMLLT is the first small molecule chemical probe for the YEATS domain (YD) of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3) with Kd of 129 and 77 nM respectively, IC50 of 0.26 uM (MLLT1).
SGC-iMLLT is a potent and selective inhibitor of MLLT1/3-histone interaction.
SGC-iMLLT dsiplays excellent selectivity over other human YD proteins (YEATS2/4) and bromodomains.
