You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Bromodomain-BRD-IN-26
BRD-IN-26

Chemical Structure : BRD-IN-26

CAS No.: 1915012-19-9

BRD-IN-26 (PB1(5) inhibitor)

Catalog No.: PC-62277Not For Human Use, Lab Use Only.

BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 (PB1(5)) with a KD of 124 nM, SMARCA2B and SMARCA4 with KD values of 262 and 417 nM, respectively.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 (PB1(5)) with a KD of 124 nM, SMARCA2B and SMARCA4 with KD values of 262 and 417 nM, respectively.
    BRD-IN-26 displays excellent selectivity over other bromodomains.

    Physicochemical Properties

    M.Wt 330.816
    Formula C17H19ClN4O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-6-chloro-3-((4-methylpiperazin-1-yl)methylene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one

    References

    1. Sutherell CL, et al. J Med Chem. 2016 May 26;59(10):5095-101.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: