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Chemical Structure : BPTF inhibitor BZ1
Catalog No.: PC-72758Not For Human Use, Lab Use Only.
BPTF inhibitor BZ1 is a potent, selective, cell-active inhibitor of bromodomain PHD finger transcription factor (BPTF) with Kd of 6.3 nM, >350-fold selectivity over BET bromodomains.
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BPTF inhibitor BZ1 is a potent, selective, cell-active inhibitor of bromodomain PHD finger transcription factor (BPTF) with Kd of 6.3 nM, >350-fold selectivity over BET bromodomains.
BPTF inhibitor BZ1 sensitizes 4T1 breast cancer cells to doxorubicin but not BPTF knockdown cells, suggesting a specificity to BPTF.
| M.Wt | 278.74 | |
| Formula | C13H15ClN4O | |
| Appearance | Solid | |
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1. Huda Zahid, et al. J Med Chem. 2021 Sep 23;64(18):13902-13917.
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