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Chemical Structure : BBC1115
Catalog No.: PC-20838Not For Human Use, Lab Use Only.
BBC1115 is a novel chemotype inhibitor of bromodomain and extra-terminal motif (BET) proteins, displays broad binding across BDs of BET proteins.
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BBC1115 is a novel chemotype inhibitor of bromodomain and extra-terminal motif (BET) proteins, displays broad binding across BDs of BET proteins.
BBC1115 is structurally distinct from known BET inhibitors.
BBC1115 treatment resulted in a typical response to BET inhibitors, represented by suppression of MYC programs and dissociation of BRD4 from chromatin.
BBC1115 suppresses BET-dependent gene expression programs and exhibits anti-proliferative activity in vitro and in vivo.
| M.Wt | 539.60 | |
| Formula | C28H27F2N3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Seoyeon Jeong, et al. Mol Ther Nucleic Acids. 2023 Apr 24;32:637-649.
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