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Cat. No. Product Name CAS No. Information
PC-61482

TAI-95

1438638-83-5 TAI-95 (TAI 95) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines).
PC-61480

INH154

1587705-63-2 INH154 is a novel small molecules disrupting Hec1/Nek2 interaction, inhibits HeLa and MDA-MB-468 cancer cells growth with IC50 of 0.20 and 0.12 uM, respectively.
PC-42194

INH-6

1001753-24-7 A small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.
PC-61484

HCI-2389

A potent, specific, irreversible NIMA-related Kinase 2 (NEK2) inhibitor with IC50 of 16.65 nM.
PC-61483

Nek2 inhibitor (R)-21

1364269-10-2 A potent and selective NIMA-related Kinase 2 (NEK2) inhibitor with IC50 of 22 nM, >200-fold selectivity over Plk1, Mps1, Aurora A and CDK2.
PC-61481

TAI-1

1334921-03-7 A potent, small molecule Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=13.48 nM K562 cells).
PC-61479

Nek2 inhibitor 72

A potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM.

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