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Chemical Structure : Nek2 inhibitor V8
Catalog No.: PC-20888Not For Human Use, Lab Use Only.
Nek2 inhibitor V8 is a novel spirocyclic selective, reversible inhibitor of NIMA Related Kinase 2 (Nek2) kinase with IC50 of 2.4 uM, attenuates pAkt/PI3K signaling.
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Nek2 inhibitor V8 is a novel spirocyclic selective, reversible inhibitor of NIMA Related Kinase 2 (Nek2) kinase with IC50 of 2.4 uM, attenuates pAkt/PI3K signaling.
Nek2 inhibitor V8 attenuates proliferative and migratory phenotypes of highly aggressive human MDA-MB-231 breast and A549 lung cancer cell lines.
| M.Wt | 386.26 | |
| Formula | C14H16BrN3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bhuiyan AI, et al. Bioorg Med Chem Lett. 2023 May 15;88:129288.
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