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Nek2 inhibitor 72

Chemical Structure : Nek2 inhibitor 72

CAS No.:

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Nek2 inhibitor 72

Catalog No.: PC-61479Not For Human Use, Lab Use Only.

Nek2 inhibitor 72 is a potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Nek2 inhibitor 72 is a potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM.
    Nek2 inhibitor 72 displays >10-fold selectivity over CDK2.

    Physicochemical Properties

    M.Wt 334.427
    Formula C19H22N6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-6-(2-(azepan-1-yl)vinyl)-N-phenyl-9H-purin-2-amine

    References

    1. Coxon CR, et al. Oncotarget. 2017 Mar 21;8(12):19089-19124.

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