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Cat. No. Product Name Information
PC-70002

MIV-6R

menin-MLL inhibitor

MIV-6R is a potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM.
PC-60001

PF-06821497 S enantiomer

PF-06821497 S enantiomer is a novel potent, selective, orally bioavailable EZH2 inhibitor with Ki of <0.1 and 1.15 nM aginast both wt and mutant Y641N EZH2, respectively.
PC-45679

XY1

XY1 is the inactive control compound of SGC-707, shows no inhibition on PRMT3.
PC-45465

UNC1079

UNC1079 is the piperidine analog of UNC1021, structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies (L3MBTL3 of >10 uM by AlphaScreen, >1000-fold weaker than UNC1215).
PC-45680

SGC707

PRMT3 inhibitor

SGC707 (SGC 707) is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM, Kd=53 nM).
PC-45658

MS023

type I PRMTs inhibitor

MS023 is a potent, selective, and cell-active inhibitor of type I PRMTs with IC50s of 30/119/83/4/5 nM for PRMT1/3/4/6/8 respectively.
PC-45727

MI-538

Menin-MLL inhibitor

MI-538 is potent and selective menin-MLL interaction inhibitor (IC50=21 nM).
PC-45726

MI-463

Menin-MLL inhibitor

MI-463 is a highly potent and orally bioavailable small-molecule inhibitor of menin-MLL (IC50=15.3 nM, Kd=9.9 nM).
PC-42673

BIX-01294

G9a inhibitor

BIX-01294 is a specific small molecule G9a histone methyltransferase inhibitor with IC50 of 1.7 uM.
PC-45576

AMI-1

PRMTs inhibitor

AMI-1 (Arginine methyltransferase inhibitor 1) is a specific inhibitor of PRMTs (protein arginine methyltransferases), but not lysine methyltransferases.
PC-45050

BRD-4770

HMTase inhibitor

A SAM mimetic that selectively inhibits a subset of Histone Methyltransferase (HMTs), including G9a, in biochemical assays and in cells.
PC-44291

UNC0638

G9a/GLP inhibitor

UNC0638 (UNC 0638) is a potent, selective, substrate-competitive inhibitor of G9a (EHMT2) and GLP (EHMT1) with IC50 of <15 nM and 19 nM in SAHH-coupled assays, respectively,

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