Catalog No.: PC-62316Not For Human Use, Lab Use Only.
UM171 (UM-171) is a potent agonist of human hematopoietic stem cell (HSC) self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM.
UM171 (UM-171) is a potent agonist of human hematopoietic stem cell (HSC) self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM.
UM171 modulates the CoREST complex and causes LSD1 degradation, potentiates the activity of a CULLIN3-E3 ubiquitin ligase (CRL3) complex.
UM171 triggers Cul3-KBTBD4-mediated degradation of ELM2 domain-harboring proteins.
UM171 (UM-171) enables a robust ex vivo expansion of human CB cells with functionally validated long-term in vivo repopulating capability.
