| Cat. No. |
Product Name |
Information |
| PC-45092 |
MI-503
Menin-MLL inhibitor
|
MI-503 (MI 503) is a highly potent and orally bioavailable small-molecule inhibitor of Menin-MLL interaction with Kd of 9.3 nM. |
| PC-42907 |
3-Deazaneplanocin A hydrochloride
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) hydrochloride is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42587 |
3-Deazaneplanocin A
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42923 |
MM-102 trifluoroacetate
MLL1/WDR5 inhibitor
|
MM-102 trifluoroacetate is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-42922 |
MM-102
MLL1/WDR5 inhibitor
|
MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-45489 |
PFI-2 hydrochloride
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) hydrochloride is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-45488 |
PFI-2
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-26542 |
EP102
METTL3 inhibitor
|
EP102 is a potent, selective METTL3 inhibitor with IC50 of 2 nM in SPA primary assay. |
| PC-26532 |
METTL16-IN-1
METTL16 inhibitor
|
METTL16-IN-1 is a specific small molecule METTL16 inhibitor with IC50 of 1.7 uM against the METTL16-RNA binding. |
| PC-26383 |
(+)SHIN2
SHMT1/2 inhibitor
|
(+)SHIN2 is a folate-competitive, cell-permeable inhibitor of human SHMT1/2 with improved pharmacokinetic properties over SHIN1. |
| PC-26366 |
WDR5 oligomerization inducer WZ-1
WDR5 oligomerization inducer
|
WZ-1 is a selective WDR5 oligomerization inducer, binds the WBM site of WDR5 and reacts with Cys248 to form an intramolecular disulfide, triggers oligomerization via thio-disulfide exchange, disrupting WDR5 interactions at both WIN and WBM sites. |
| PC-26274 |
SGSS05NS
SETD8 inhibitor
|
SGSS05NS is a potent, selective and covalent inhibitor of protein lysine methyltransferase (PKMT) SETD8 with IC50 of 0.54 uM, covalently modifies SETD8 at Cys311. |
