| Cat. No. |
Product Name |
Information |
| PC-62309 |
A-395
PRC2 EED inhibitor
|
A-395 (A395) is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM. |
| PC-62142 |
ML399
Menin-MLL inhibitor
|
ML399 (VU0516340) is a potent and cell penetrant menin-MLL inhibitor with IC50 of 90 nM. |
| PC-61791 |
PR5-LL-CM01
PRMT5 inhibitor
|
PR5-LL-CM01 is a novel selective, small-molecule inhibitor of PRMT5 methyltransferase with IC50 of 7.5 uM. |
| PC-61403 |
Valemetostat
EZH1/EZH2 inhibitor
|
Valemetostat (DS-3201, DS3201) is a potent, selective, dual EZH1/EZH2 inhibitor with IC50 <10 nM. |
| PC-61209 |
EPZ 025654
CARM1 inhibitor
|
EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM. |
| PC-70359 |
TM2-115
|
TM2-115 is a BIX-01294 derivative that inhibit malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death. |
| PC-61030 |
EZM 2302
CARM1 inhibitor
|
EZM 2302 (EZM2302, GSK 3359088) is a potent, selective, orally available arginine methyltransferase CARM1 inhibitor with IC50 of 6 nM, with broad selectivity against other HMTases. |
| PC-60541 |
(R)-OR-S1
|
(R)-OR-S1 is a potent, selective, orally bioavailable EZH1/2 dual inhibitor with IC50 of 7.4/10 nM, inhibits H3K27me3 in HCT116 cells with IC50 of 0.47 nM. |
| PC-60423 |
A-893
SMYD2 inhibitor
|
A-893 (A893) is a potent, selective and cell active lysine methyltransferase SMYD2 inhibitor with IC50 of 2.8 nM. |
| PC-60420 |
BAY-598
SMYD2 inhibitor
|
BAY-598 (BAY598) is a potent, selective, and cell-active, substrate-competitive inhibitor of SMYD2 with IC50 of 27±7 nM in the biochemical SPA assay. |
| PC-70164 |
EML633
SPIN1 inhibitor
|
EML633 (EML 633) small-molecule inhibitor of methyllysine reader protein SPIN1 (Spindlin 1) with Kd of 2 uM. |
| PC-70163 |
EML631
SPIN1 inhibitor
|
EML631 (EML 631) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 4 uM. |
