Catalog No.: PC-62981Not For Human Use, Lab Use Only.
CMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival, without effect on normal B cells.
CMP-5 (PRMT5-IN-5) is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival, without effect on normal B cells.
CMP-5 (PRMT5-IN-5) displays no activity against other type I (PRMT1 and PRMT4) and type II (PRMT7) enzymes.
CMP-5 (PRMT5-IN-5) for inhibition of PRMT5 leads to lost recruitment of a PRMT5/p65/HDAC3-repressive complex on the miR96 promoter, restored miR96 expression, and PRMT5 downregulation.
