| Cat. No. |
Product Name |
Information |
| PC-43259 |
GSK503
EZH2 inhibitor
|
GSK503 is a potent, specific EZH2 methyltransferase inhibitor that inhibits the methyltransferase activity of WT and mutant EZH2 with similar potency (Ki app=3-27 nM). |
| PC-43184 |
CARM1-IN-7g
CARM1 inhibitor
|
CARM1-IN-7g is a potent, selective coactivator-associated arginine methyltransferase 1 (CARM1) with IC50 of 8.6 uM, exhibits lower or no activity against a panel of different PRMTs or HKMTs (>80-fold over PRMT1 and SET7). |
| PC-43165 |
EPZ015666
PRMT5 inhibitor
|
EPZ015666 (GSK3235025) is a potent, selective, orally available inhibitor of PRMT5 with Ki/IC50 of 5/22 nM, displays broad selectivity against a panel of other histone methyltransferases. |
| PC-63229 |
PJ-68
PRMT5 inhibitor
|
PJ-68 is a potent, selective inhibitor of arginine methyltransferase PRMT5 with IC50 of 517 nM, shows no inhibitory activity against type I PRMT family members ( (PRMT1, 3, 4, 6, and 8). |
| PC-43110 |
A-366
G9a/GLP inhibitor
|
A-366 is a potent, highly selective inhibitor of histone methyltransferase G9a/GLP with IC50 of 3/38 nM, >1,000-fold selectivity for G9a over 21 other methyltransferases. |
| PC-42984 |
UNC0379 trifluoroacetate
SETD8 inhibitor
|
UNC0379 trifluoroacetate is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 with IC50 of 7.3 uM. |
| PC-42983 |
UNC0379
SETD8 inhibitor
|
UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 with IC50 of 7.3 uM. |
| PC-63136 |
MS012
G9a-like protein inhibitor
|
MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases.. |
| PC-63135 |
MS0124
G9a-like protein inhibitor
|
MS-0124 is a potent and selective inhibitor of G9a-like Protein (GLP) lysine methyltransferase with IC50 of 13 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases.. |
| PC-63022 |
G9a inhibitor E72
G9a/GLP inhibitor
|
G9a inhibitor E72 (E-72) is a potent inhibitor of histone H3K9 methyltransferases G9a and G9a-like protein (GLP) with Kd of 136 nM and 164 nM, shows selectivity over the related H3K9 methyltransferase Suv39H2. |
| PC-62981 |
CMP-5
PRMT5 inhibitor
|
CMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival, without effect on normal B cells. |
| PC-62980 |
CMP-5 hydrochloride
PRMT5 inhibitor
|
CMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival, without effect on normal B cells. |
