| Cat. No. |
Product Name |
Information |
| PC-42097 |
EPZ-015866
PRMT5 inhibitor
|
EPZ-015866 (GSK-591, GSK-3203591) is a potent, selective protein methyltransferase 5 (PRMT5) inhibitor with IC50 of 4 nM. |
| PC-42198 |
SGC2085
CARM1 inhibitor
|
SGC2085 is a potent, selective protein arginine methyltransferase PRMT4 (CARM1) inhibitor with IC50 of 50 nM, displays >100-fold selectivity over other PRMTs (PRMT6 IC50=5.3 uM). |
| PC-42272 |
UNC3866
CBX7 inhibitor
|
UNC3866 is a potent, selective PRC1 chromodomains antagonist that binds to CBX4 and CBX7 with Kd of 100 nM. |
| PC-42740 |
UNC0224
G9a/GLP inhibitor
|
UNC0224 (UNC-0224) is a potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM in biochemical assays. |
| PC-42081 |
A-196
SUV420H1 inhibitor
|
A-196 is a potent, selective and substrate-competitive inhibitor of protein lysine methyltransferases (PKMTs) SUV420H1 and SUV420H2 with IC50 of 25 nM and 144 nM, respectively. |
| PC-45598 |
LLY-507
SMYD2 inhibitor
|
LLY-507 is a potent, selective and cell-active inhibitor of SMYD2 (IC50<15 nM). |
| PC-45617 |
WDR5-0103
MLL1-WDR5 inhibitor
|
A potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay. |
| PC-45602 |
MI-136
menin-MLL inhibitor
|
MI-136 is a potent Menin-MLL interaction inhibitor with IC50 of 31 nM. |
| PC-44607 |
UNC1215
L3MBTL3 inhibitor
|
UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM. |
| PC-42037 |
HLCL-61 hydrochloride
PRMT5 inhibitor
|
HLCL-61 hydrochloride is a potent and selective protein arginine methyltransferase PRMT5 inhibitor. |
| PC-42741 |
UNC0321
G9a inhibitor
|
UNC0321 (UNC-0321) is a highly potent, selective histone methyltransferase G9a inhibitor with Ki of 63 pM. |
| PC-45092 |
MI-503
Menin-MLL inhibitor
|
MI-503 (MI 503) is a highly potent and orally bioavailable small-molecule inhibitor of Menin-MLL interaction with Kd of 9.3 nM. |
