SGC707 | PRMT3 inhibitor | Probechem Biochemicals

Chemical Structure : SGC707

CAS No.: 1687736-54-4

SGC707 (SGC-707)

Catalog No.: PC-45680Not For Human Use, Lab Use Only.

SGC707 (SGC 707) is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM, Kd=53 nM).

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$138	In stock
50 mg	$218	In stock
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Biological Activity

SGC707 (SGC 707) is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM, Kd=53 nM).
SGC707 shows outstanding selectivity against 31 other methyltransferases and more than 250 non-epigenetic targets.
SGC707 is active in cells, also bioavailable and suitable for animal studies.

Physicochemical Properties

M.Wt	298.3397
Formula	C16H18N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Urea, N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-

References

1. Kaniskan HU, et al. Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70.

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SGC707 (SGC-707)

Biological Activity

Physicochemical Properties

References

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