Chemical Structure : SGC707
CAS No.: 1687736-54-4
Catalog No.: PC-45680Not For Human Use, Lab Use Only.
SGC707 (SGC 707) is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM, Kd=53 nM).
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SGC707 (SGC 707) is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM, Kd=53 nM).
SGC707 shows outstanding selectivity against 31 other methyltransferases and more than 250 non-epigenetic targets.
SGC707 is active in cells, also bioavailable and suitable for animal studies.
M.Wt | 298.3397 | |
Formula | C16H18N4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Urea, N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]- |
1. Kaniskan HU, et al. Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70.
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