| Cat. No. |
Product Name |
Information |
| PC-26591 |
NSUN2 inhibitor AK
NSUN2 inhibitor
|
NSUN2 inhibitor AK (AK-968/36977265) is a small molecule inhibitor of RNA methyltransferase NSUN2, decreases m5C occupancy and GATM mRNA levels, shows anti-fibrotic efficacy. |
| PC-26589 |
UNC7242
PHF1/PHF19 inhibitor
|
UNC7242 is a small molecule antagonist of PRC2 components PHF1 and PHF19 with ITC Kd of 1.13 uM and 0.64 uM, displaces recombinant or endogenous PHF1 or 19 from nucleosomes. |
| PC-26542 |
EP102
METTL3 inhibitor
|
EP102 is a potent, selective METTL3 inhibitor with IC50 of 2 nM in SPA primary assay. |
| PC-26532 |
METTL16-IN-1
METTL16 inhibitor
|
METTL16-IN-1 is a specific small molecule METTL16 inhibitor with IC50 of 1.7 uM against the METTL16-RNA binding. |
| PC-26496 |
C191-0266
METTL3 inhibitor
|
C191-0266 is a small molecule inhibitor of METTL3 with KD of 7.28 uM and enzymatic IC50 of 7.84 uM. |
| PC-26384 |
METTL9i
METTL9 inhibitor
|
METTL9i is a first-in-class, highly potent, selective and cell-active methyltransferase METTL9 inhibitor with IC50 of 67 nM. |
| PC-26274 |
SGSS05NS
SETD8 inhibitor
|
SGSS05NS is a potent, selective and covalent inhibitor of protein lysine methyltransferase (PKMT) SETD8 with IC50 of 0.54 uM, covalently modifies SETD8 at Cys311. |
| PC-26273 |
MS4138
SETD8 inhibitor
|
MS4138 is a potent, selective and covalent inhibitor of protein lysine methyltransferase (PKMT) SETD8 with IC50 of 1.4 uM, covalently modifies SETD8 at Cys311. |
| PC-26271 |
MS2928
SETD8 inhibitor
|
MS2928 is a potent and selective SETD8 covalent inhibitor, inhibits SETD8 methyltransferase activity with IC50 of 0.14 uM, covalently modifies SETD8 at Cys311. |
| PC-26182 |
AC1Q3QWB
HOTAIR-EZH2 inhibitor
|
AC1Q3QWB (AQB) is a selective and efficient inhibitor of HOTAIR-EZH2 interaction with IC50 of 42.47 nM, exhibits potent anti-tumor activity in cancer cells expressing high levels of HOTAIR and EZH2. |
| PC-26021 |
YL-5092
YTHDC1 inhibitor
|
YL-5092 is a highly potent and selective, first-in-class inhibitor of RNA m6A reader YTHDC1 with IC50 of 7.4 nM and SPR Kd of 29.6 nM. |
| PC-25966 |
SKLB06489
Type I PRMTs inhibitor
|
SKLB06489 is a potent, selective type I PRMTs inhibitor with IC50 of 64.55, 4.21, and 51.27 nM for PRMT1, PRMT6, and PRMT8 respectively. |
