| Cat. No. |
Product Name |
Information |
| PC-20002 |
UNC2327
PRMT3 inhibitor
|
UNC2327 (UNC-2327) is a potent, allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with IC50 of 230 nM. |
| PC-49859 |
DS-1594a
Menin-MLL1 inhibitor
|
DS-1594a (Emilumenib) is a highly potent Menin-MLL1 inhibitor with IC50 of 1.4 nM in cell-free AlphaLISA assays, displays selective growth inhibition against AML and ALL cells with MLL1-r or NPM1c. |
| PC-49814 |
SMYD3 inhibitor 49
SMYD3 inhibitor
|
SMYD3 inhibitor 49 is a potent and selective SMYD3 inhibitor with IC50 of 6.3 and 44 nM in biochemical and cellular MEKK2me assays, respectively. |
| PC-49813 |
EM127
SMYD3 inhibitor
|
EM127 is a potent, site-specific covalent, second-generation inhibitor of SMYD3 methyltransferase. |
| PC-49729 |
BRD9539
G9a inhibitor
|
BRD9539 is a small molecule inhibitor of histone hethyltransferase of G9a (euchromatin histone methyltransferase 2, EHMT2) with IC50 of 6.3 uM. |
| PC-49728 |
UNC0642
G9a/GLP inhibitor
|
UNC0642 (UNC 0642) is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor with IC50 of <2.5 nM. |
| PC-49724 |
JS1310
PRMT7 inhibitor
|
JS1310 (JS-1310) is a specific small-molecule PRMT7 inhibitor with IC50 of 5 uM (human PRMT7), displays no acitivity against type I PRMTs (PRMT1, 3, 4, 6, and 8, IC50 >100 uM) or the type II PRMT5 (IC50=50 uM). |
| PC-49699 |
SKLB-03220
EZH2 inhibitor
|
SKLB-03220 (SKLB03220) is a potent, selective EZH2 covalent inhibitor with IC50 of 1.72 nM (EZH2 WT). |
| PC-49683 |
CDIBA
METTL3-14 inhibitor
|
CDIBA is an allosteric inhibitors of m6A-RNA methyltransferase, METTL3 -14 complex with IC50 of 17.3 uM, also reported as a cytosolic phospholipase A2 (cPLA2) inhibitor. |
| PC-49679 |
METTL3 inhibitor UZH2
METTL3 inhibitor
|
METTL3 inhibitor UZH2 is a potent, selective and cell-permeable RNA methyltransferase METTL3 inhibitor with IC50 of 5 nM in TR-FRET assays. |
| PC-49674 |
IHMT-337
EZH2 inhibitor
|
IHMT-337 (IHMT337) is a potent, highly selective and irreversible EZH2 inhibitor, specifically inhibits the methylation at H3K27. |
| PC-49612 |
RK-701
G9a/GLP inhibitor
|
RK-701 (RK701) is a potent, highly selective and reversible histone lysine methyltransferases G9a and G9a-like protein (GLP) inhibitor with IC50 of 23-27 nM and 53 nM, respectively. |
