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UNC7648

Chemical Structure : UNC7648

CAS No.:

UNC7648 (UNC 7648)

Catalog No.: PC-21490Not For Human Use, Lab Use Only.

UNC7648 is a small molecule inhibitor of the methyl-lysine reader p53 binding protein 1 (53BP1) tandem Tudor domain (TTD) with TR-FRET IC50 of 8.6 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UNC7648 is a small molecule inhibitor of the methyl-lysine reader p53 binding protein 1 (53BP1) tandem Tudor domain (TTD) with TR-FRET IC50 of 8.6 uM.

Physicochemical Properties

M.Wt 611.79
Formula C35H45N7O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-((2'-((1-amino-1-oxo-6-(pyrrolidin-1-yl)hexan-2-yl)carbamoyl)-[1,1'-biphenyl]-2-yl)methyl)-4-(4-methylpiperazin-1-yl)picolinamide

References

1. Devan J Shell, et al. SLAS Discov. 2022 Dec;27(8):428-439.

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