UNC7648 | 53BP1 inhibitor | Probechem Biochemicals

Chemical Structure : UNC7648

UNC7648 (UNC 7648)

Catalog No.: PC-21490Not For Human Use, Lab Use Only.

UNC7648 is a small molecule inhibitor of the methyl-lysine reader p53 binding protein 1 (53BP1) tandem Tudor domain (TTD) with TR-FRET IC50 of 8.6 uM.

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Biological Activity

UNC7648 is a small molecule inhibitor of the methyl-lysine reader p53 binding protein 1 (53BP1) tandem Tudor domain (TTD) with TR-FRET IC50 of 8.6 uM.

Physicochemical Properties

M.Wt	611.79
Formula	C35H45N7O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-((2'-((1-amino-1-oxo-6-(pyrrolidin-1-yl)hexan-2-yl)carbamoyl)-[1,1'-biphenyl]-2-yl)methyl)-4-(4-methylpiperazin-1-yl)picolinamide

References

1. Devan J Shell, et al. SLAS Discov. 2022 Dec;27(8):428-439.

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UNC7648 (UNC 7648)

Biological Activity

Physicochemical Properties

References

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