| Cat. No. |
Product Name |
Information |
| PC-42907 |
3-Deazaneplanocin A hydrochloride
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) hydrochloride is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42587 |
3-Deazaneplanocin A
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42923 |
MM-102 trifluoroacetate
MLL1/WDR5 inhibitor
|
MM-102 trifluoroacetate is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-42922 |
MM-102
MLL1/WDR5 inhibitor
|
MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-45489 |
PFI-2 hydrochloride
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) hydrochloride is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-45488 |
PFI-2
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-23905 |
CSV0C018875
G9a inhibitor
|
CSV0C018875 is a cell active quinoline based G9a inhibitor with IC50 of 67.02 uM. |
| PC-23904 |
HKMTI-1-248
G9a/GLP inhibitor
|
HKMTI-1-248 is a potent and selective G9a/GLP inhibitor with IC50 of 13 nM (G9a), equipotent against G9a and GLP (G9a-like protein, EHMT1). |
| PC-23903 |
EPZ035544
G9a/GLP inhibitor
|
EPZ035544 is a potent inhibitor of histone methyltransferase G9a/GLP with IC50 of 10 nM/<100 nM respectively. |
| PC-23902 |
ZZM-1220
G9a/GLP inhibitor
|
ZZM-1220 is a potent, selective G9a/GLP covalent inhibitor with IC50 of 458/924 nM respectively. |
| PC-23669 |
ND-L11B
NSD2 degrader
|
ND-L11B is an effective degrader of RE-IIBP and NSD2-long, effectively induces NSD2 degradation with DC50 of 1.48 and 0.80 uM in KMS11 MM cell line, reduces H3K36me2 level in cancer cells. |
| PC-23666 |
Rabdosiin
METTL8 inhibitor
|
Rabdosiin is a tetramer of caffeic acid isolated from the stem of Ocimum sanctum, shows anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase, also is a potential METTL8 inhibitor. |
