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Cat. No. Product Name Information
PC-42922

MM-102

MLL1/WDR5 inhibitor

MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.
PC-45489

PFI-2 hydrochloride

SETD7 inhibitor

PFI-2 ((R)-PFI-2) hydrochloride is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively.
PC-45488

PFI-2

SETD7 inhibitor

PFI-2 ((R)-PFI-2) is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively.
PC-24375

CM112

PRMT1 degrader

CM112 is a potent, selective PRMT1 degrader designed by tethering adamantane to MS023 via a 5-PEG linker, has DC50 of 0.83 uM in MCF-7 cells.
PC-24337

iZMYND8-34

ZMYND8 inhibitor

iZMYND8-34 is a small molecule inhibitor of histone reader zinc finger MYND-type containing 8 (ZMYND8), inhibits ZMYND8 histone recognition, effectively blocks neuroendocrine prostate cancer (NEPC) development.
PC-24327

NSD3 inhibitor A8

NSD3 inhibitor

NSD3 inhibitor A8 is a potent small molecule inhibitor of nuclear receptor-binding SET domain protein 3 (NSD3) with IC50 of 0.7 uM, inhibits NSD1 and NSD2 with IC50 of 1.5 uM and 0.9 uM respectively.
PC-24292

Dual CARM1-IKZF3 inhibitor 074

CARM1/IKZF3 inhibitor

Dual CARM1-IKZF3 inhibitor 074 is a compound composed of the CARM1 inhibitor EZM2302, linked to pomalidomide, increases CRBN-dependent IKZF1, IKZF3, ZFP91, and FGD3 protein degradation, inhibits CRAM1 with IC50 of 2 nM.
PC-24232

Nsun2‐i4

NSUN2 inhibitor

Nsun2‐i4 is a specific small molecule inhibitor of m5C methyltransferase NSUN2 with KD of 2.65 uM in MST assays.
PC-24113

Balomenib

Menin-KMT2A inhibitor

Balomenib (Balamenib, ZE63-0302) is an oral small molecule inhibitor of the menin-KMT2A interaction.
PC-24105

YTHDF2 Inhibitor CK-75

YTHDF2 inhibitor

YTHDF2 Inhibitor CK-75 is a specific small molecule inhibitor of YTHDF2, potentially binds to a small hydrophobic pocket on the YTH domain (KD=26.2 uM), potently inhibits the protein-RNA interaction of YTHDF2.
PC-24018

STC-15

METTL3 inhibitor

STC-15 is a small molecule, orally active inhibitor of RNA methyltransferase METTL3, restrains cancer growth and induces anti-cancer immunity.
PC-24065

MS9024

DNMT1 degrader

MS9024 is a potent, selective PROTAC degrader of DNA methyltransferase 1 (DNMT1) with DC50 of 40 nM in HCT116 cells, Dmax=89%.

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