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Cat. No. Product Name Information
PC-24327

NSD3 inhibitor A8

NSD3 inhibitor

NSD3 inhibitor A8 is a potent small molecule inhibitor of nuclear receptor-binding SET domain protein 3 (NSD3) with IC50 of 0.7 uM, inhibits NSD1 and NSD2 with IC50 of 1.5 uM and 0.9 uM respectively.
PC-24292

Dual CARM1-IKZF3 inhibitor 074

CARM1/IKZF3 inhibitor

Dual CARM1-IKZF3 inhibitor 074 is a compound composed of the CARM1 inhibitor EZM2302, linked to pomalidomide, increases CRBN-dependent IKZF1, IKZF3, ZFP91, and FGD3 protein degradation, inhibits CRAM1 with IC50 of 2 nM.
PC-24232

Nsun2‐i4

NSUN2 inhibitor

Nsun2‐i4 is a specific small molecule inhibitor of m5C methyltransferase NSUN2 with KD of 2.65 uM in MST assays.
PC-24113

Balomenib

Menin-KMT2A inhibitor

Balomenib (Balamenib, ZE63-0302) is an oral small molecule inhibitor of the menin-KMT2A interaction.
PC-24105

YTHDF2 Inhibitor CK-75

YTHDF2 inhibitor

YTHDF2 Inhibitor CK-75 is a specific small molecule inhibitor of YTHDF2, potentially binds to a small hydrophobic pocket on the YTH domain (KD=26.2 uM), potently inhibits the protein-RNA interaction of YTHDF2.
PC-24018

STC-15

METTL3 inhibitor

STC-15 is a small molecule, orally active inhibitor of RNA methyltransferase METTL3, restrains cancer growth and induces anti-cancer immunity.
PC-24065

MS9024

DNMT1 degrader

MS9024 is a potent, selective PROTAC degrader of DNA methyltransferase 1 (DNMT1) with DC50 of 40 nM in HCT116 cells, Dmax=89%.
PC-24017

STM3006

METTL3 inhibitor

STM3006 is a potent, selective second-generation METTL3 inhibitor with IC50 of 5 nM, stimulates a cell-intrinsic interferon response through dsRNA formation and promotes antitumor immunity.
PC-24016

EP652

METTL3 inhibitor

EP652 is a potent, selective and in vivo active inhibitor of RNA methyltransferase METTL3 with IC50 of 2 nM (METTL3/14) in SPA primary assays.
PC-23957

DDD1870799

RNMT inhibitor

DDD1870799 is a small molecule inhibitor o fHsRNMT (RNA guanine-7 methyltransferase)-RAM (RNA guanine-N7 methyltransferase activating subunit) complex, binds competitively with cap and binds effectively to HsRNMT-RAM in the presence of the co-product SAM wth Kd of 2.5 uM.
PC-23956

DDD1060606

RNMT inhibitor

DDD1060606 is a small molecule inhibitor o fHsRNMT (RNA guanine-7 methyltransferase)-RAM (RNA guanine-N7 methyltransferase activating subunit) complex, binds competitively with cap and binds effectively to HsRNMT-RAM in the presence of the co-product SAM wth Kd of 1.6 uM.
PC-23905

CSV0C018875

G9a inhibitor

CSV0C018875 is a cell active quinoline based G9a inhibitor with IC50 of 67.02 uM.

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