UNC1215 |CAS:1415800-43-9 Probechem Biochemicals

Chemical Structure : UNC1215

CAS No.: 1415800-43-9

UNC1215 (UNC 1215;UNC-1215)

Catalog No.: PC-44607Not For Human Use, Lab Use Only.

UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.

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10 mg	$98	In stock
25 mg	$158	In stock
50 mg	$248	In stock
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Biological Activity

UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.
UNC1215 is 50-fold more potent toward L3MBTL3 than other members of the MBT family.
UNC1215 directly binds to L3MBTL3 via the Kme-binding pocket of the MBT domains.

Physicochemical Properties

M.Wt	529.7161
Formula	C32H43N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 270 mg/mL
Chemical Name/SMILES	Methanone, 1,1'-[2-(phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]-

References

1. James LI, et al. Nat Chem Biol. 2013 Mar;9(3):184-91.

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UNC1215 (UNC 1215;UNC-1215)

Biological Activity

Physicochemical Properties

References

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