Chemical Structure : UNC1215
CAS No.: 1415800-43-9
Catalog No.: PC-44607Not For Human Use, Lab Use Only.
UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.
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UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.
UNC1215 is 50-fold more potent toward L3MBTL3 than other members of the MBT family.
UNC1215 directly binds to L3MBTL3 via the Kme-binding pocket of the MBT domains.
M.Wt | 529.7161 | |
Formula | C32H43N5O2 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 270 mg/mL |
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Chemical Name/SMILES |
Methanone, 1,1'-[2-(phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]- |
1. James LI, et al. Nat Chem Biol. 2013 Mar;9(3):184-91.
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