MI-136 |CAS:1628316-74-4 Probechem Biochemicals

Chemical Structure : MI-136

CAS No.: 1628316-74-4

MI-136 (MI 136;MI136)

Catalog No.: PC-45602Not For Human Use, Lab Use Only.

MI-136 is a potent Menin-MLL interaction inhibitor with IC50 of 31 nM.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
25 mg	$248	In stock
50 mg	$428	In stock
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Biological Activity

MI-136 is a potent Menin-MLL interaction inhibitor with IC50 of 31 nM.
MI-136 demonstrates potent inhibitory activity and strong binding affinity to menin.

Physicochemical Properties

M.Wt	470.5132
Formula	C23H21F3N6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 31 mg/mL
Chemical Name/SMILES	1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-

References

1. Borkin D, et al. J Med Chem. 2016 Feb 11;59(3):892-913.

2. Borkin D, et al. Cancer Cell. 2015 Apr 13;27(4):589-602.

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MI-136 (MI 136;MI136)

Biological Activity

Physicochemical Properties

References

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