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Chemical Structure : MIV-6R
Catalog No.: PC-70002Not For Human Use, Lab Use Only.
MIV-6R is a potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM.
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MIV-6R is a potent, ligand-efficient, and cell-active inhibitor menin-MLL interaction with IC50 of 56 nM, Kd of 85 nM.
MIV-6R demonstrateds strong and selective effects in MLL leukemia cells, and induces more pronounced increase in CD11b expression in MLL-AF9 BMCs.
| M.Wt | 417.5863 | |
| Formula | C27H35N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14.
2. He S, et al. J Med Chem. 2014 Feb 27;57(4):1543-56.
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