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Chemical Structure : LEM-14
CAS No.: 1814881-70-3
Catalog No.: PC-35849Not For Human Use, Lab Use Only.
LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $168 | In stock | |
| 10 mg | $288 | In stock | |
| 25 mg | $488 | In stock | |
| 100 mg | Get quote |
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LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.
| M.Wt | 478.567 | |
| Formula | C25H26N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-2-((4-(1-oxoisochromane-3-carbonyl)piperazin-1-yl)methyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one |
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1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4.
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