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Chemical Structure : VinSpinIn
Catalog No.: PC-35846Not For Human Use, Lab Use Only.
VinSpinIn is a potent, cell active chemical probe for the Spin family protein with Kd of 10-130 nM for across the family, displays >300-fold selectivity over a panel of methyltransferases.
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VinSpinIn is a potent, cell active chemical probe for the Spin family protein with Kd of 10-130 nM for across the family (SPIN1, Kd=9.9 nM), displays >300-fold selectivity over a panel of methyltransferases.
VinSpinIn demonstrates dose dependant inhibition of the Spin1-H3 interaction in a NanoBRET cellular target engagement assay.
| M.Wt | 738.978 | |
| Formula | C42H58N8O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1 Fagan V, et al. J Med Chem. 2019 Oct 24;62(20):9008-9025.
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