MS012 | G9a-like protein inhibitor | Probechem Biochemicals

Chemical Structure : MS012

MS012 (MS 012)

Catalog No.: PC-63136Not For Human Use, Lab Use Only.

MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases..

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Biological Activity

MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases.

Physicochemical Properties

M.Wt	401.555
Formula	C22H35N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N2-Hexyl-6,7-dimethoxy-N4-(1-methylpiperidin-4-yl)quinazoline2,4-diamine

References

1. Xiong Y, et al. J Med Chem. 2017 Mar 9;60(5):1876-1891.

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MS012 (MS 012)

Biological Activity

Physicochemical Properties

References

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