MS0124 | GLP inhibitor | Probechem Biochemicals

Chemical Structure : MS0124

CAS No.: 1197196-63-6

MS0124 (MS 0124)

Catalog No.: PC-63135Not For Human Use, Lab Use Only.

MS-0124 is a potent and selective inhibitor of G9a-like Protein (GLP) lysine methyltransferase with IC50 of 13 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases..

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Biological Activity

MS-0124 is a potent and selective inhibitor of G9a-like Protein (GLP) lysine methyltransferase with IC50 of 13 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases.

Physicochemical Properties

M.Wt	387.484
Formula	C20H29N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morpholinoquinazolin-4-amine

References

1. Xiong Y, et al. J Med Chem. 2017 Mar 9;60(5):1876-1891.

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MS0124 (MS 0124)

Biological Activity

Physicochemical Properties

References

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