Chemical Structure : STM3006
CAS No.: 2499664-52-5
Catalog No.: PC-24017Not For Human Use, Lab Use Only.
STM3006 is a potent, selective second-generation METTL3 inhibitor with IC50 of 5 nM, stimulates a cell-intrinsic interferon response through dsRNA formation and promotes antitumor immunity.
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STM3006 is a potent, selective second-generation METTL3 inhibitor with IC50 of 5 nM, stimulates a cell-intrinsic interferon response through dsRNA formation and promotes antitumor immunity.
M.Wt | 519.45 | |
Formula | C25H27BrN8 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
6-Bromo-4-(1-((6-((4,4-dimethylpiperidin-1-yl)methyl)imidazo[1,2-a]pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-1H-indazole |
1. Andrew A Guirguis, et al. Cancer Discov. 2023 Oct 5;13(10):2228-2247.
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