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STM3006

Chemical Structure : STM3006

CAS No.: 2499664-52-5

STM3006 (STM-3006)

Catalog No.: PC-24017Not For Human Use, Lab Use Only.

STM3006 is a potent, selective second-generation METTL3 inhibitor with IC50 of 5 nM, stimulates a cell-intrinsic interferon response through dsRNA formation and promotes antitumor immunity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

STM3006 is a potent, selective second-generation METTL3 inhibitor with IC50 of 5 nM, stimulates a cell-intrinsic interferon response through dsRNA formation and promotes antitumor immunity.

Physicochemical Properties

M.Wt 519.45
Formula C25H27BrN8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Bromo-4-(1-((6-((4,4-dimethylpiperidin-1-yl)methyl)imidazo[1,2-a]pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-1H-indazole

References

1. Andrew A Guirguis, et al. Cancer Discov. 2023 Oct 5;13(10):2228-2247.

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