Chemical Structure : DDD1870799
Catalog No.: PC-23957Not For Human Use, Lab Use Only.
DDD1870799 is a small molecule inhibitor o fHsRNMT (RNA guanine-7 methyltransferase)-RAM (RNA guanine-N7 methyltransferase activating subunit) complex, binds competitively with cap and binds effectively to HsRNMT-RAM in the presence of the co-product SAM wth Kd of 2.5 uM.
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DDD1870799 is a small molecule inhibitor o fHsRNMT (RNA guanine-7 methyltransferase)-RAM (RNA guanine-N7 methyltransferase activating subunit) complex, binds competitively with cap and binds effectively to HsRNMT-RAM in the presence of the co-product SAM wth Kd of 2.5 uM.
M.Wt | 354.39 | |
Formula | C19H19FN4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Pearson LA, et al. Biochem J. 2025 Jan 27:BCJ20240608.
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