A-395N |CAS:2096983-62-7 Probechem Biochemicals

Chemical Structure : A-395N

A-395N (A395N)

Catalog No.: PC-62310Not For Human Use, Lab Use Only.

A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM..

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Biological Activity

A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM.

Physicochemical Properties

M.Wt	442.62
Formula	C24H34N4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3R,4S)-1-benzyl-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine

References

1. He Y, et al. Nat Chem Biol. 2017 Apr;13(4):389-395.

2. Cancer Discov. 2017 Apr;7(4):OF8. doi: 10.1158/2159-8290.CD-RW2017-030.

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A-395N (A395N)

Biological Activity

Physicochemical Properties

References

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