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Chemical Structure : ML399
Catalog No.: PC-62142Not For Human Use, Lab Use Only.
ML399 (VU0516340) is a potent and cell penetrant menin-MLL inhibitor with IC50 of 90 nM.
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ML399 (VU0516340) is a potent and cell penetrant menin-MLL inhibitor with IC50 of 90 nM.
ML399 (VU0516340) shows improved potency and DMPK properties.
ML399 (VU0516340) is a chemical probe for in vivo proof-of-mechanism studies.
| M.Wt | 445.538 | |
| Formula | C27H28FN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Senter T, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Senter T, et al. Bioorg Med Chem Lett. 2015 Jul 1;25(13):2720-5.
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