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Chemical Structure : UNC-2170
CAS No.: 1648707-58-7
Catalog No.: PC-62384Not For Human Use, Lab Use Only.
UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
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|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $458 | In stock | |
| 100 mg | Get quote |
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UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
UNC-2170 is highly cell permeant with no significant measureable cellular efflux.
UNC-2170 shows modestly potent, demonstrates at least 17-fold selectivity for 53BP1 as compared to nine other Kme reader proteins.
| M.Wt | 313.23 | |
| Formula | C14H21BrN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-bromo-N-(3-(tert-butylamino)propyl)benzamide |
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1. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81.
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