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DS79932728

Chemical Structure : DS79932728

CAS No.: 2757191-62-9

DS79932728 (DS 79932728)

Catalog No.: PC-23812Not For Human Use, Lab Use Only.

DS79932728 is a potent and orally bioavailable histone lysine methyltransferase EHMT2/1 (G9a/GLP) inhibitor with IC50 of 12.6/75.7 nM respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DS79932728 is a potent and orally bioavailable histone lysine methyltransferase EHMT2/1 (G9a/GLP) inhibitor with IC50 of 12.6/75.7 nM respectively.

Physicochemical Properties

M.Wt 311.43
Formula C19H25N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5'-methoxy-6'-(1-methyl-2,5,6,7-tetrahydro-1H-azepin-4-yl)spiro[cyclobutane-1,3'-indol]-2'-amine

References

1. Katayama K, et al. ACS Med Chem Lett. 2020 Dec 28;12(1):121-128.

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