Farnesoid X Receptor (FXR) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofFarnesoid X Receptor (FXR) Farnesoid X Receptor (FXR)

Cat. No.	Product Name	Information
PC-23132	Dual FXR-LIFR modulator 3a LIFR antagonist/FXR agonist	Dual FXR-LIFR modulator 3a is a first-in-class hybrid leukemia inhibitory factor receptor (LIFR) inhibitor and Farnesoid X receptor (FXR) agonist with IC50 of 2.0 uM and EC50 of 3.2 uM respectively, protects against the development of acute liver fibrosis and inflammation.
PC-22657	Agmatine sulfate FXR agonist	Agmatine sulfate is a microbial metabolite derived from arginine by arginine decarboxylase, activates the farnesoid X receptor (FXR) pathway to subsequently inhibit glucagon-like peptide-1 (GLP-1) secretion by L cells.
PC-22169	F44-A13 FXR antagonist	F44-A13 is a highly selective farnesoid X receptor (FXR) antagonist with IC50 of 1.1 uM, with high selectivity over eleven other nuclear receptors.
PC-20980	HPG1860 FXR agonist	HPG1860 is a potent, selective, nonbile acid full FXR agonist with EC50 of 5 nM and 18 nM in FR-FRET and luciferase assays, respectively.
PC-20979	MET409 FXR agonist	MET409 (MET-409) is a potent, selective farnesoid X receptor (FXR) agonist with EC50 of 16 nM (human FXR).

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