| Cat. No. |
Product Name |
Information |
| PC-60080 |
GSK2324
FXR agonist
|
GSK2324 (GSK 2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay. |
| PC-60079 |
LY2562175
FXR agonist
|
LY2562175 (TERN-101) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM. |
| PC-60056 |
Tropifexor
FXR agonist
|
Tropifexor (LJN-452, LJN452) is a novel highly potent, selective, orally acitive FXR full agonist with EC50 of 0.26 nM. |
| PC-42734 |
Fexaramine
FXR agonist
|
Fexaramine is a potent, specific FXR agonist with EC50 of 25 nM, more efficacious ligand for FXR than GW4064. |
| PC-45980 |
Chenodeoxycholic Acid
FXR agonist
|
Chenodeoxycholic Acid (CDCA) is a potent natural bile acid at stimulating the nuclear bile acid receptor, farnesoid X receptor (FXR). |
| PC-45825 |
GW-4064
FXR agonist
|
GW-4064 (GW4064) is a potent and selective FXR agonist with EC50 of 15 nM in cell-free assay, >200-fold more potent than CDCA. |
| PC-42924 |
INT-747
FXR agonist
|
INT-747 (Obeticholic acid, 6-ECDCA, 6-Ethylchenodeoxycholic acid) is a potent and selective FXR agonist (EC50=99 nM). |
| PC-45904 |
Turofexorate isopropyl
FXR agonist
|
Turofexorate isopropyl (WAY-362450, XL335, FXR-450) is a highly potent, selective, and orally active agonist of FXR with EC50 of 4 nM. |
| PC-26702 |
PX20606
FXR agonist
|
PX20606 (PX-102) is a potent, selective FXR agonist with EC50 of 771 nM, 237 nM and 129 nM for mouse, rat, and human FXR in biochemical TR-FRET assays. |
| PC-26701 |
Fexaramine-3
FXR agonist
|
Fexaramine-3 (Fex-3, Fex3) is a potent, selective intestinal-restricted FXR agonist. significantly promotes the mRNA expression of BSEP and SHP and suppresses CYP7A1, all of which are the target genes of FXR. |
| PC-26301 |
Altenusin
FXR agonist
|
Altenusin (2076A) is a nonsteroidal fungal metabolite and potent, selective agonist of Farnesoid X receptor (FXR) with EC50 of 3.2 uM. |
| PC-25964 |
Linafexor
FXR agonist
|
Linafexor (CS0159) is a potent, selective and orally bioavailable agonist of farnesoid X receptor (FXR). |
