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Request The Product List ofFarnesoid X Receptor (FXR) Farnesoid X Receptor (FXR)

Cat. No. Product Name CAS No. Information
PC-61390

Nidufexor

1773489-72-7 Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders.
PC-61368

Cilofexor

1418274-28-8 Cilofexor (GS-9674, GS9674, PX-104) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.
PC-60080

GSK-2324

1020567-30-9 GSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay.
PC-60079

LY-2562175

1103500-20-4 LY-2562175 (LY2562175, LY 2562175) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM.
PC-60056

Tropifexor

1383816-29-2 Tropifexor (LJN-452, LJN452) is a novel highly potent, selective, orally acitive FXR full agonist with EC50 of 0.26 nM.
PC-42924

INT-747

459789-99-2 INT-747(Obeticholic acid, 6-ECDCA, 6-Ethylchenodeoxycholic acid) is a potent and selective FXR agonist (EC50=99 nM).
PC-38044

EDP-305

1933507-63-1 EDP-305 (EDP305) is a potent, selective, nonbile acid farnesoid X receptor (FXR) agonist with antifibrotic effect.

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