PDL103 | Dual FXR/GPBAR1 antagonist | Probechem Biochemicals

Chemical Structure : PDL103

Catalog No.: PC-20484Not For Human Use, Lab Use Only.

PDL103 is a potent, dual FXR/GPBAR1 antagonist with IC50 of 10 and 19 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDL103 is a potent, dual FXR/GPBAR1 antagonist with IC50 of 10 and 19 uM, respectively.

M.Wt	426.29
Formula	C23H17Cl2NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	OCC1=CC=C(C2=CC=C(OCC3=CC(C4=C(Cl)C=CC=C4Cl)=NO3)C=C2)C=C1

1. Di Giorgio C, et al. Front Oncol. 2023 Mar 14;13:1140730.