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VU6083859

Chemical Structure : VU6083859

CAS No.:

VU6083859

Catalog No.: PC-25989Not For Human Use, Lab Use Only.

VU6083859 is a potent, selective The thousand and one (TAO) kinase TAOK1 inhibitor with IC50 of 158 nM, shows 22- and >63-fold selectivity over TAOK2 and TAOK3.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU6083859 is a potent, selective The thousand and one (TAO) kinase TAOK1 inhibitor with IC50 of 158 nM, shows 22- and >63-fold selectivity over TAOK2 and TAOK3.

Physicochemical Properties

M.Wt 467.49
Formula C26H24F3N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(3-oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(2-(trifluoromethyl)pyridin-4-yl)benzamide

References

1. Schultz DC, et al. ACS Chem Neurosci. 2026 Jan 13. doi: 10.1021/acschemneuro.5c00906.

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