| Cat. No. |
Product Name |
Information |
| PC-62729 |
SW-034538
TAOK2 inhibitor
|
SW-034538 is a potent TAOK2 (Thousand-And-One Kinase 2; MAP3K17) inhibitor with IC50 of 300 nM, has cross-reactivity with respect to six of the 45 kinases (Raf1, GSK3β, JNK1, IRAK4, HGK and CDK2). |
| PC-62728 |
SW-083688
TAOK2 inhibitor
|
SW-083688 (SW083688) is a potent, highly selective TAOK2 (Thousand-And-One Kinase 2, MAP3K17) inhibitor with IC50 of 1.3 uM. |
| PC-62726 |
GSK-114
TNNI3K inhibitor
|
GSK-114 is a potent, selective TNNI3K (TNNI3 Interacting Kinase) inhibitor with IC50 of 25 nM, dispalys 40-fold over B-Raf, exceptional broad spectrum kinase selectivity (IC50>1,000 nM, 99% of kinases, 291/294). |
| PC-62541 |
MEKK2 inhibitor 1s
MEKK2 inhibitor
|
MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies. |
| PC-60165 |
MAP3K14-IN-173
NIK inhibitor
|
MAP3K14-IN-173 is a novel potent MAP3K14 kinase (NF-κB-inducing kinase, NIK) inhibitor with IC50 of 1.8 nM (NIK autophosphorylation). |
| PC-60150 |
ASK1-IN-19
ASK1 inhibitor
|
AKS1-IN-19 is a novel potent, selective and orally active ASK1 (MAP3K5) inhibitor with pIC50 of 8.3. |
| PC-70030 |
Tpl2-1
Tpl2/MAP3K8 inhibitor
|
Tpl2-1 is a potent, selective, reversible and ATP-competitive inhibitor of Tpl2 kinase (Cot/MAP3K8) with IC50 of 50 nM. |
| PC-60092 |
GNE-8505
DLK inhibitor
|
GNE-8505 (GNE8505) is a potent, selective and CNS-penetrant inhibitor of dual leucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. |
| PC-45651 |
NQDI-1
ASK1 inhibitor
|
NQDI-1 is a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with Ki of 500 nM. |
| PC-45794 |
KIN001-266
Tpl2/MAP3K8 inhibitor
|
Tpl2-IN-34 is a potent, selective Tpl2 (cot/MAP3K8) inhibitor with IC50 of 1.6 nM. |
| PC-45565 |
Selonsertib
ASK1 inhibitor
|
Selonsertib (GS-4997) is a highly selective and potent, ATP-competetive inhibitor of ASK1 (Apoptosis Signal-regulating Kinase 1, MAP3K5) with pIC50 of 8.3. |
| PC-23614 |
KAI-11101
DLK inhibitor
|
KAI-11101 is a potent, selective, brain-penetrant dual leucine zipper kinase (DLK, MAP3K12) inhibitor with Ki of 0.7 nM and cellular p-JNK IC50 of 51 nM. |
