SW-034538 (SW034538)

Chemical Structure : SW-034538

Catalog No.: PC-62729Not For Human Use, Lab Use Only.

SW-034538 is a potent TAOK2 (Thousand-And-One Kinase 2; MAP3K17) inhibitor with IC50 of 300 nM, has cross-reactivity with respect to six of the 45 kinases (Raf1, GSK3β, JNK1, IRAK4, HGK and CDK2).

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Biological Activity

SW-034538 (SW034538) is a potent TAOK2 (Thousand-And-One Kinase 2; MAP3K17) inhibitor with IC50 of 300 nM, has cross-reactivity with respect to six of the 45 kinases (Raf1, GSK3β, JNK1, IRAK4, HGK and CDK2).

Physicochemical Properties

M.Wt	404.503
Formula	C18H20N4O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-((2,5-dimethoxyphenyl)amino)-4'-methyl-[4,5'-bithiazol]-2'-yl)propionamide

References

1. Piala AT, et al. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3923-7.

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