Catalog No.: PC-62726Not For Human Use, Lab Use Only.
GSK-114 is a potent, selective TNNI3K (TNNI3 Interacting Kinase) inhibitor with IC50 of 25 nM, dispalys 40-fold over B-Raf, exceptional broad spectrum kinase selectivity (IC50>1,000 nM, 99% of kinases, 291/294).
GSK-114 is a potent, selective TNNI3K (TNNI3 Interacting Kinase) inhibitor with IC50 of 25 nM, dispalys 40-fold over B-Raf, exceptional broad spectrum kinase selectivity (IC50>1,000 nM, 99% of kinases, 291/294).
GSK-114 has adequate oral exposure to enable its use in cellular and in vivo studies.
