MEKK2 inhibitor 1s | Probechem Biochemicals

Chemical Structure : MEKK2 inhibitor 1s

MEKK2 inhibitor 1s (MEKK2-IN-1s)

Catalog No.: PC-62541Not For Human Use, Lab Use Only.

MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.

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Biological Activity

MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.
MEKK2 inhibitor 1s displays activity in cell-based assays in which it inhibited ERK5 pathway activation in cells and inhibited cell migration in a scratch assay.

Physicochemical Properties

M.Wt	338.363
Formula	C19H18N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-8-ethoxy-2-((4-hydroxy-2-methylphenyl)imino)-2H-chromene-3-carboxamide

References

1. Ahmad S, et al. Biochem Biophys Res Commun. 2018 Jan 29;496(1):205-211.

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MEKK2 inhibitor 1s (MEKK2-IN-1s)

Biological Activity

Physicochemical Properties

References

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