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Chemical Structure : MEKK2 inhibitor 1s
Catalog No.: PC-62541Not For Human Use, Lab Use Only.
MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.
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MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.
MEKK2 inhibitor 1s displays activity in cell-based assays in which it inhibited ERK5 pathway activation in cells and inhibited cell migration in a scratch assay.
| M.Wt | 338.363 | |
| Formula | C19H18N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ahmad S, et al. Biochem Biophys Res Commun. 2018 Jan 29;496(1):205-211.
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