Chemical Structure : Selonsertib
CAS No.: 1448428-04-3
Catalog No.: PC-45565Not For Human Use, Lab Use Only.
Selonsertib (GS-4997) is a highly selective and potent, ATP-competetive inhibitor of ASK1 (Apoptosis Signal-regulating Kinase 1, MAP3K5) with pIC50 of 8.3.
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M.Wt | 445.4921 | |
Formula | C24H24FN7O | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 31 mg/mL |
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Chemical Name/SMILES |
Benzamide, 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]- |
1. Lin JH, et al. Nephron. 2015;129(1):29-33.
2. Ji N, et al. Cancer Lett. 2019 Jan;440-441:82-93.
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