MEKK (MAP3K) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-23614	KAI-11101 DLK inhibitor	KAI-11101 is a potent, selective, brain-penetrant dual leucine zipper kinase (DLK, MAP3K12) inhibitor with Ki of 0.7 nM and cellular p-JNK IC50 of 51 nM.
PC-22734	Tpl2/MAP3K8 inhibitor 33 Tpl2/MAP3K8 inhibitor	Tpl2/MAP3K8 inhibitor 33 is a potent, selective inhibitor of cancer osaka thyroid (COT) kinase (Tpl2, MAP3K8) with IC50 of 4 nM.
PC-22733	Tpl2/MAP3K8 inhibitor 32 Tpl2/MAP3K8 inhibitor	Tpl2/MAP3K8 inhibitor 32 is a potent, selective inhibitor of cancer osaka thyroid (COT) kinase (Tpl2, MAP3K8) with IC50 of 6 nM.
PC-22729	Tpl2-2 Tpl2/MAP3K8 inhibitor	Tpl2-2 (TPL2 Kinase Inhibitor II) is a cell-permeable naphthyridine-cyclohexyl Tpl2-1 analog that acts as a potent ATP-competitive Tpl2 inhibitor (IC50 =160 nM).

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