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(±)-trans-BAS-2

Chemical Structure : (±)-trans-BAS-2

CAS No.: 2790482-16-3

(±)-trans-BAS-2

Catalog No.: PC-26983Not For Human Use, Lab Use Only.

(±)-trans-BAS-2 is a potent, highly selective HDAC6 inhibitor with IC50 of 462 nM (hHDAC6), is more active than cis-BAS-2 (IC50=16.9 uM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

(±)-trans-BAS-2 is a potent, highly selective HDAC6 inhibitor with IC50 of 462 nM (hHDAC6), is more active than cis-BAS-2 (IC50=16.9 uM).

Physicochemical Properties

M.Wt 283.39
Formula C13H21N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ethanone, 2-[[(3aR,7aR)-3a,4,5,6,7,7a-hexahydro-1H-benzimidazol-2-yl]thio]-1-(4-morpholinyl)-, rel-

References

1. Rodrigues DA, et al. Nat Commun. 2026 Jun 5. doi: 10.1038/s41467-026-73146-5.

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