(R)-(-)-Rolipram |CAS:85416-75-7 Probechem Biochemicals

Chemical Structure : (R)-(-)-Rolipram

CAS No.: 85416-75-7

Catalog No.: PC-45081Not For Human Use, Lab Use Only.

A more active enantiomer of the PDE4 inhibitor rolipram.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A more active enantiomer of the PDE4 inhibitor rolipram; shows 2-10-fold more potent than the S-(+) enantiomer rolipram.

Asthma

Phase 2 Clinical

M.Wt	275.3428
Formula	C16H21NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 49 mg/mL
Chemical Name/SMILES	2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4R)-

1. Schneider HH, et al. Eur J Pharmacol. 1986 Aug 7;127(1-2):105-15.

2. Owens RJ, et al. Biochem J. 1997 Aug 15;326 ( Pt 1):53-60.

3. Ohsawa F, et al. Jpn J Pharmacol. 1998 Jun;77(2):147-54.