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(R)-DNMDP

Chemical Structure : (R)-DNMDP

CAS No.: 1630760-60-9

(R)-DNMDP (DNMDP R-form)

Catalog No.: PC-62885Not For Human Use, Lab Use Only.

(R)-DNMDP (DNMDP R-form) is the R-form of is DNMDP, which is a potent and selective cancer cell cytotoxic agent that binds to PDE3A, promotes an interaction between PDE3A and Schlafen 12 (SLFN12).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    (R)-DNMDP (DNMDP R-form) is the R-form of is DNMDP, which is a potent and selective cancer cell cytotoxic agent that binds to PDE3A, promotes an interaction between PDE3A and Schlafen 12 (SLFN12).

    Physicochemical Properties

    M.Wt 304.35
    Formula C15H20N4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-6-(4-(diethylamino)-3-nitrophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

    References

    1. de Waal L, et al. Nat Chem Biol. 2016 Feb;12(2):102-8.

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