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(R)-Flurbiprofen

Chemical Structure : (R)-Flurbiprofen

CAS No.: 51543-40-9

(R)-Flurbiprofen (E7869, Tarenflurbil, MPC7869)

Catalog No.: PC-42511Not For Human Use, Lab Use Only.

(R)-Flurbiprofen (E7869, Tarenflurbil, MPC7869) is a non-steroidal anti-inflammatory drug (NSAID) and cyclooxygenase (COX) inhibitor, also inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

(R)-Flurbiprofen (E7869, Tarenflurbil, MPC7869) is a non-steroidal anti-inflammatory drug (NSAID) and cyclooxygenase (COX) inhibitor, also inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 uM.

Physicochemical Properties

M.Wt 244.2609
Formula C15H13FO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (αR)-

References

1. Chalmers IM, et al. Ann Rheum Dis. 1972 Jul;31(4):319-24.

2. King JG Jr, et al. Oncogene. 2001 Oct 18;20(47):6864-70.

3. Peretto I, et al. J Med Chem. 2005 Sep 8;48(18):5705-20.

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