Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : (R)-LMI
Catalog No.: PC-38308Not For Human Use, Lab Use Only.
(R)-LMI (H2N-R-Leu-Met-Ile-COOH) is a tripeptide analogue of corticotropin-releasing factor (CRF) and CRF antagonist targeting the N-domain of CRF1 receptor.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
(R)-LMI (H2N-R-Leu-Met-Ile-COOH) is a tripeptide analogue of corticotropin-releasing factor (CRF) and CRF antagonist targeting the N-domain of CRF1 receptor.
(R)-LMI inhibits CRF-stimulated cAMP accumulation with IC50 of 1.7 uM.
(R)-LMI inhibits the production of interleukins by adipocytes and the proliferation rate of RAW 264.7 cells.
| M.Wt | 375.53 | |
| Formula | C17H33N3O4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. George Liapakis, et al. Amino Acids. 2020 Sep;52(9):1337-1351.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
