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(R)-LMI

Chemical Structure : (R)-LMI

CAS No.:

(R)-LMI (H2N-R-Leu-Met-Ile-COOH)

Catalog No.: PC-38308Not For Human Use, Lab Use Only.

(R)-LMI (H2N-R-Leu-Met-Ile-COOH) is a tripeptide analogue of corticotropin-releasing factor (CRF) and CRF antagonist targeting the N-domain of CRF1 receptor.

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    Biological Activity

    (R)-LMI (H2N-R-Leu-Met-Ile-COOH) is a tripeptide analogue of corticotropin-releasing factor (CRF) and CRF antagonist targeting the N-domain of CRF1 receptor.
    (R)-LMI inhibits CRF-stimulated cAMP accumulation with IC50 of 1.7 uM.
    (R)-LMI inhibits the production of interleukins by adipocytes and the proliferation rate of RAW 264.7 cells.

    Physicochemical Properties

    M.Wt
    Formula
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    Chemical Name/SMILES

    References

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