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Chemical Structure : (R)-OF-NB1
Catalog No.: PC-21397Not For Human Use, Lab Use Only.
(R)-OF-NB1 is a small molecule splice variant GluN2B-selective NMDAR antagonist with IC50 of 675 nM and 97 nM for F-NB1 for splice variant containing exon 5 and GluN1-1a in X. laevis oocytes.
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(R)-OF-NB1 is a small molecule splice variant GluN2B-selective NMDAR antagonist with IC50 of 675 nM and 97 nM for F-NB1 for splice variant containing exon 5 and GluN1-1a in X. laevis oocytes.
(R)-OF-NB1 clearly discriminates the two splice variants, GluN1-1a and GluN1-1b.
| M.Wt | 329.42 | |
| Formula | C20H24FNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ritter N, et al. Mol Neurobiol. 2023 Dec;60(12):7238-7252.
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