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(S)-10-Hydroxycamptothecin

Chemical Structure : (S)-10-Hydroxycamptothecin

CAS No.: 19685-09-7

(S)-10-Hydroxycamptothecin (10-HCPT)

Catalog No.: PC-25441Not For Human Use, Lab Use Only.

(S)-10-Hydroxycamptothecin (10-HCPT, 10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor with remarkable apoptosis-inducing effect, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

(S)-10-Hydroxycamptothecin (10-HCPT, 10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor with remarkable apoptosis-inducing effect, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration.

Physicochemical Properties

M.Wt 364.36
Formula C20H16N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

References

1. Tian Y, et al. J Cell Mol Med. 2025 Sep;29(17):e70815.

2. Zhang XW, et al. Acta Pharmacol Sin. 2000 Apr;21(4):364-8.

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